Lynda is a Shire Patient Ambassador. Read her story here.

GATTEX® (teduglutide [rDNA origin]) for Injection is a prescription medicine used in adults with Short Bowel Syndrome (SBS) who need additional nutrition or fluids from intravenous (IV) feeding (parenteral support).
Lynda is a real patient
taking GATTEX.

LYNDA'S STORY

Lynda's Story

Lynda’s journey to diagnosis

Lynda is retired now, but she had an exciting career as a social worker in the Red Cross during the Vietnam War and later worked as a jewelry and women’s accessories sales rep.

Lynda’s SBS journey began in 2009, when she and her husband got lost in the New Mexico desert for four days without food or water. The temperatures reached 107 degrees Fahrenheit; and by the time they were finally rescued, Lynda’s bowels had turned necrotic, and surgeons had to remove a good portion of her intestines. At the time, Lynda was grateful to be alive.

A year later, Lynda had a bowel obstruction and had to have more of her intestines removed. When she came out of surgery, doctors told her that she had 10 to 12 inches of small intestine left and she was diagnosed with Short Bowel Syndrome (SBS).

Lynda’s experience with parenteral support (PS)

When Lynda’s doctors explained SBS to her, they told her that her body wasn’t absorbing the nutrients she needed and that she’d be getting all of her nutrients from total parenteral nutrition (TPN). She was fitted for a PICC line before she left the hospital. Lynda was on TPN and hydration 17 hours a day, seven days a week for two years. She and her doctor eventually got it down to 15 hours a day, seven days a week.

Learning about GATTEX®

Lynda's doctor first told her about  GATTEX. He explained the science of it and told her it's a prescription medicine used in adults with Short Bowel Syndrome who need additional nutrition or fluids from PS.

Lynda was excited to learn that GATTEX might help her reduce the amount of volume and days on TPN. Her doctor talked her through all the things she could expect, including the risk of possible serious side effects — like making abnormal cells grow faster, blockage of the bowel, and fluid overload.

What would a day off PS mean to you?

GATTEX was studied in a 6-month clinical trial of 86 adult SBS patients who needed to use
PS at least 3 times a week for at least 1 year. GATTEX helped the majority of patients:

Weekly PS volume
Reduce weekly PS volume

GATTEX 63% reduced PS by 20% or more

Placebo 30% reduced PS by 20% or more

Weekly PS
Get more day(s) off weekly PS

GATTEX 54% achieved at least 1 day off PS

Placebo 23% achieved at least 1 day off PS

This is Lynda's story.

More day(s) off my PN

Less IV time keeping me from friends

Lynda is a real patient
taking GATTEX.

Lynda’s healthcare team reduced her PS volume over time

Over time, under the supervision of her doctor, after Lynda started on GATTEX, her TPN went from seven times a week, to five, to three…until eventually, she was on no TPN and no PICC line! And that’s where she still is today: no TPN, no tubes, and no backpack.

This is what Lynda experienced, but keep in mind, not all patients who take GATTEX will wean off their infusions. Lynda continues to work closely with her doctor to monitor her condition and keep an eye out for side effects. She has experienced swelling in her abdomen that her doctor thinks may be a side effect of GATTEX.

Spending less time infusing gives Lynda freedom to do the things she enjoys

Now that Lynda’s off of TPN, she gets to spend more time with family and friends instead of being hooked up to TPN. She’s learned to value and adore the people she loves even more, and she appreciates the little things: whether it’s a funny card or a picture of her grandkids or taking a ride in her classic car.

GATTEX was also studied in a 24-month study. 76 of the 78 patients who completed the first study decided to participate in the extension study. They were joined by an additional 12 adults who were receiving PS at least 3 times a week for at least one year, for a total of 88 participants. All of the people in this study knew they were taking GATTEX.

Weekly PS volume
After 24 months:

55%

reduced their PS volume
by 20% or more

After 30 months:

93%

reduced their PS volume
by 20% or more

30 people completed a total of 2.5 years of GATTEX treatment.
(They took GATTEX in study 1 and GATTEX in study 2.)

29 patients completed 2 years of GATTEX treatment.
(They took placebo in study 1, then GATTEX in study 2.)

In the same clinical trial, GATTEX helped patients get more day(s) off weekly PS.
After completing 30 months of GATTEX treatment:

Weekly PS

70%

achieved at least 1 day off per week
(21 out of 30 patients)

Weekly PS

60%

achieved at least 3 days off per week
(18 out of 30 patients)

Weekly PS

33%

weaned off PS completely (10 out of 30 patients)

Not all patients who take GATTEX will wean off parenteral support. Individual results may vary.

SBS Connect logo

Want to talk with someone who takes GATTEX?

If you’re living with SBS or you care for someone who does, you aren’t alone. Schedule a call with a GATTEX Patient Ambassador through our mentor program, SBS Connect, or see if there’s a live event in an area near you.

Sign up for a call

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Important Safety Information: GATTEX may cause serious side effects including making abnormal cells grow faster, polyps in the colon (large intestine), blockage of the bowel (intestines), swelling (inflammation) or blockage of your gallbladder or pancreas, and fluid overload.
Click here for additional Important Safety Information.