Peggy is a Shire Patient Ambassador. Read her story here.

GATTEX® (teduglutide [rDNA origin]) for Injection is a prescription medicine used in adults with Short Bowel Syndrome (SBS) who need additional nutrition or fluids from intravenous (IV) feeding (parenteral support).
Peggy is a real patient
taking GATTEX.


Peggy's Story

Peggy’s journey to diagnosis

Peggy enjoys spending time with her husband and two dogs. Like many members of her family, she was drawn to science and worked in biomedical research for 25 years.

She was diagnosed with Crohn’s disease as a young teenager and had multiple bowel resections. Over the years, more and more of her intestines had to be removed and she had an ileostomy. After another resection, her remaining bowel came to little more than two feet and her surgeon diagnosed her with SBS. After her diagnosis, Peggy began receiving two liters of IV hydration twice a week with magnesium.

Learning about GATTEX®

When Peggy’s doctor learned about GATTEX, he was excited and called her on Christmas Eve to discuss it. He encouraged her to read about this prescription medicine used in adults with Short Bowel Syndrome who need additional nutrition or fluids from IV feeding online to learn about the possible benefits and serious risks, including abnormal cell growth, polyps in the colon and bowel blockage.

She had undergone surgery to get rid of strictures to reduce the risk of further obstructions. So at first, Peggy wasn’t ready to commit to GATTEX because she was worried about the possibility of going through a blockage of the bowel all over again.

Ultimately, Peggy decided to try GATTEX because of her father who had recently passed away. He was a scientist and was very interested in GATTEX from both scientific and personal standpoints. He thought there was a chance GATTEX might help his daughter. Peggy thought she owed it to her father to learn more about, and potentially try, GATTEX. After she talked with her doctor about the possible side effects, she decided to give it a shot.

What would a day off PS mean to you?

GATTEX was studied in a 6-month clinical trial of 86 adult SBS patients who needed to use
PS at least 3 times a week for at least 1 year. GATTEX helped the majority of patients:

Weekly PS volume
Reduce weekly PS volume

GATTEX 63% reduced PS by 20% or more

Placebo 30% reduced PS by 20% or more

Weekly PS
Get more day(s) off weekly PS

GATTEX 54% achieved at least 1 day off PS

Placebo 23% achieved at least 1 day off PS

This is Peggy's story.

More day(s) off IV hydration

Less time infusing on vacation

Peggy is a real patient
taking GATTEX.

Peggy’s healthcare team reduced her PS volume over time

Under the supervision of her infusion nurse, she was able to reduce her IV hydration from routinely getting two liters twice a week to regularly getting one liter once a week. Instead of spending five hours twice a week travelling to the infusion clinic to get her hydration, she now spends four hours, once per week, to get her hydration.

Everyone will respond differently to treatment. This has been Peggy’s experience and yours may be different. Peggy continues to work closely with her doctor to monitor her condition and keep an eye out for side effects. She has experienced blockage of the bowel, a bloated feeling and redness at the injection site.

Spending less time infusing gives Peggy freedom to do the things she enjoys

Now that Peggy is spending less time infusing IV hydration, she has time for travel and to be with friends, but most importantly, she’s been able to re-engage in some volunteer activities that had been important to her in the past and have always given her a sense of fulfillment.

SBS Connect logo

Want to talk with someone who takes GATTEX?

If you’re living with SBS or you care for someone who does, you aren’t alone. Schedule a call with a GATTEX Patient Ambassador through our mentor program, SBS Connect, or see if there’s a live event in an area near you.

Sign up for a call

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Important Safety Information: GATTEX may cause serious side effects including making abnormal cells grow faster, polyps in the colon (large intestine), blockage of the bowel (intestines), swelling (inflammation) or blockage of your gallbladder or pancreas, and fluid overload.
Click here for additional Important Safety Information.