Learn about short bowel syndrome (SBS), a rare malabsorption disorder, and why some patients may need a small bowel resection.

GATTEX® (teduglutide [rDNA origin]) for Injection is a prescription medicine used in adults with Short Bowel Syndrome (SBS) who need additional nutrition or fluids from intravenous (IV) feeding (parenteral support).


“I was eventually diagnosed with SBS after a series of surgeries to remove portions of my bowel.”

Brad, a patient living with SBS.

Short Bowel Syndrome is a serious and chronic disorder

SBS, sometimes called Short Gut Syndrome, is a serious, chronic and rare malabsorption disorder. People with SBS are unable to absorb enough nutrients and fluids from what they eat and drink alone. Malabsorption puts people at risk for diarrhea, dehydration, electrolyte disturbances and malnutrition.

Usually, people with SBS have undergone surgery to remove a large part of the intestine. After this surgery, called a bowel resection, the surface area of the intestine is decreased, which can limit the amount of nutrients and fluids the remaining intestines are able to absorb. When this happens, many patients have to receive nutrition and/or hydration through intravenous (IV) feeding, which is also called parenteral support (PS).

Why might someone need surgery to remove part of the bowel?

This chronic disease causes inflammation and possible injury to the intestines. When severe enough, treatment can include bowel resection.
Bariatric surgery, such as gastric bypass, is performed on the stomach or intestines to help people lose weight. Severe complications may require different types of bowel resections.
An injury that damages the intestine through penetration, like a gun shot, or blunt force from a car accident can lead to bowel resection.
This occurs when the blood vessels can’t deliver enough blood, including oxygen and nutrients, to the intestines to allow it to function properly. In severe cases, this can lead to tissue death, which may make it necessary to remove a portion of the bowel.
It may be necessary to remove tumors in the intestine or undergo radiation therapy during certain cancer treatments, both of which can lead to resection.
This is a twisting of the intestine. When this happens, it causes a blockage that cuts off blood flow. The damaged tissue, starved of oxygen, may need to be removed via resection.
A hernia occurs when the contents of a body cavity bulge out of the area where they are normally contained. In a strangulated hernia, the intestine that has bulged out is trapped and has its blood supply cut off. This damages the tissue, which may need to be removed via resection.
A fistula is an abnormal pathway leading from one part of the intestine to another part, to another organ in the body, or sometimes outside the body through the skin. If the fistula cannot be closed through conservative medical treatment, it may require a surgical bowel resection to prevent potential complications.

Peggy's Story

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Important Safety Information: GATTEX may cause serious side effects including making abnormal cells grow faster, polyps in the colon (large intestine), blockage of the bowel (intestines), swelling (inflammation) or blockage of your gallbladder or pancreas, and fluid overload.
Click here for additional Important Safety Information.