How to start Gattex

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Talk to your doctor

Make an appointment to see your physician.

Bring a Conversation Guide along for your discussion. It may help you and your doctor talk about whether GATTEX is right for you. You should fully understand the possible risks and benefits of treatment.

This Conversation Guide will help you ask the right questions. Take notes so you can remember what was discussed.

Download Conversation Guide
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Complete the Start Form

Once you and your doctor have decided to move forward with GATTEX, make sure you and your doctor correctly complete and sign the GATTEX Start Form. This serves as your prescription and allows OnePath® to begin working with eligible patients.

This start form should be completed with your doctor.

Download Start Form
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Connect with OnePath—personalized product support

OnePath provides product support services throughout your Shire treatment journey. From the moment you enroll in OnePath, your dedicated Patient Support Manager (PSM) will work with you one on one to help you access the treatment and support you need. You’ll also be introduced to an Onboarding & Access Specialist in your area, who will be one of your primary contacts as you get started on therapy. Once you have connected with your PSM, they will help you:

Arrange delivery of GATTEX to you or the location where you receive treatment

Learn more about OnePath.

Support with Onepath

Schedule training with a nurse educator to show you and/or your caregiver how to prepare, measure your dose, and take GATTEX according to the prescribing information

Learn more about OnePath.

Support with Onepath

How Should I inject GATTEX?

Once you are ready to begin GATTEX, be sure to follow the training provided by your healthcare provider. The instructions below show you step by step how to inject GATTEX.

Instructions for Use (IFU)

Get step-by-step instructions for injecting GATTEX. It may be helpful to print a copy and keep it with your GATTEX supplies.

Download the IFU
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How should I use GATTEX?

  • Use GATTEX exactly as your healthcare provider tells you to.
  • GATTEX is given 1 time each day at the same time.
  • Inject your dose of GATTEX under the skin (subcutaneous injection) in your stomach area (abdomen), upper legs (thighs), or upper arms. Do not inject GATTEX into a vein or muscle.
  • Use a different injection site each time you use GATTEX.
  • GATTEX comes as a powder for injection in a vial that is used only 1 time (single-use vial).The powder must be mixed with Sterile Water for Injection (a diluent) provided in a prefilled syringe before you inject it.
  • GATTEX must be injected within 3 hours after you mix it with the diluent.
  • If you miss a dose, take it as soon as you remember that day. Take your next dose the next day at the same time you take it every day.
  • Do not take 2 doses on the same day.
  • If you use more than 1 dose, call your healthcare provider right away.
  • Do not stop taking GATTEX without consulting your healthcare provider.
  • Read the Instructions for Use for detailed instructions for preparing and injecting a dose of GATTEX.

How should I store GATTEX?

  • Store GATTEX powder at room temperature up to 25°C (77°F).
  • Do not freeze GATTEX.
  • Use the GATTEX powder by the expiration date on the “Use By” sticker on the kit.
  • Use GATTEX within 3 hours after mixing it.
  • Throw away any unused GATTEX that has been mixed, even if there is medicine left in the vial.
  • Do not store any GATTEX you have mixed.

Keep GATTEX and all medicines out of the reach of children.

Learn more about OnePath.

What is GATTEX?

Important Safety Information

GATTEX may cause serious side effects including making abnormal cells grow faster, polyps in the colon (large intestine), blockage of the bowel (intestines), swelling (inflammation) or blockage of your gallbladder or pancreas, and fluid overload. Click here for additional Important Safety Information.

GATTEX® (teduglutide) for subcutaneous injection is a prescription medicine used in adults with Short Bowel Syndrome (SBS) who need additional nutrition or fluids from intravenous (IV) feeding (parenteral support).

Click here for additional Important Safety Information.

What is GATTEX?

GATTEX® (teduglutide) for subcutaneous injection is a prescription medicine used in adults with Short Bowel Syndrome (SBS) who need additional nutrition or fluids from intravenous (IV) feeding (parenteral support).

Important Safety Information

What is the most important information I should know about GATTEX?

GATTEX may cause serious side effects, including:

Making abnormal cells grow faster

GATTEX can make abnormal cells that are already in your body grow faster. There is an increased risk that abnormal cells could become cancer. If you get cancer of the bowel (intestines), liver, gallbladder or pancreas while using GATTEX, your healthcare provider should stop GATTEX. If you get other types of cancers, you and your healthcare provider should discuss the risks and benefits of using GATTEX.

Polyps in the colon (large intestine)

Polyps are growths on the inside of the colon. Your healthcare provider will have your colon checked for polyps within 6 months before starting GATTEX and have any polyps removed.

To keep using GATTEX, your healthcare provider should have your colon checked for new polyps at the end of 1 year of using GATTEX. If no polyp is found, your healthcare provider should check you for polyps as needed and at least every 5 years and have any new polyps removed. If cancer is found in a polyp, your healthcare provider should stop GATTEX.

Blockage of the bowel (intestines)

A bowel blockage keeps food, fluids, and gas from moving through the bowels in the normal way. Tell your healthcare provider right away if you have any of these symptoms of a bowel or stomal blockage:

If a blockage is found, your healthcare provider may temporarily stop GATTEX.

Swelling (inflammation) or blockage of your gallbladder or pancreas

Your healthcare provider will do tests to check your gallbladder and pancreas within 6 months before starting GATTEX and at least every 6 months while you are using GATTEX. Tell your healthcare provider right away if you get:

Fluid overload

Your healthcare provider will check you for too much fluid in your body. Too much fluid in your body may lead to heart failure, especially if you have heart problems. Tell your healthcare provider if you get swelling in your feet and ankles, you gain weight very quickly (water weight), or you have trouble breathing.

The most common side effects of GATTEX include:

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

What should I tell my healthcare provider before using GATTEX?

Tell your healthcare provider about all your medical conditions, including if you:

Tell your healthcare providers about all the medicines you take, including prescription or over-the-counter medicines, vitamins, and herbal supplements. Using GATTEX with certain other medicines may affect each other causing side effects. Your other healthcare providers may need to change the dose of any oral medicines (medicines taken by mouth) you take while using GATTEX. Tell the healthcare provider who gives you GATTEX if you will be taking a new oral medicine.

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For additional safety information, click here for full Prescribing Information.